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Testosterone Rises With Treatment for Erectile Dysfunction (ED)
(PRWEB) October 16, 2004
Men who use Viagra or Cialis for Erectile dysfunction (ED) have increases in levels of testosterone, Italian researchers report.
“We are now demonstrating the sexual and hormonal effect of two popular oral treatments for ED,” Dr. Emmanuele A. Jannini from University of L’Aquila told AMN Health. “Both were efficacious and able to increase testosterone levels after 3 months of treatment.”
Jannini team studied 74 men with erectile dysfunction and found that free and total testosterone levels rose, overall, by about 50% after treatment.
The testosterone increases were more marked in the group that took Cialis than in the Viagra group, although the drugs were equally effective in restoring sexual potency, the investigators report in the medical journal.
The frequency of full sexual intercourse was also higher with Cialis (known chemically as tadalafil), despite the use of identical numbers of pills per month, the researchers note, “strongly suggesting that the greater normalization of hormonal values in tadalafil-treated patients was due to the higher number of sexual acts.”
The higher frequency of sex “can be considered as an important benefit of tadalafil and a cost-effective advantage” for couples, the investigators suggest.
“For a man in a stable couple relationship, tadalafil is to be preferred,” Jannini commented.
In this setting, the drug can be taken twice a week to allow spontaneous sexual activity. “From a psycho-sexological point of view, this may help the patient to considered himself ‘cured’ and not simply ‘treated’ for the symptom,” he concluded.
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Study Shows Men with ED Favor Treatment with Vardenafil
Boston, MA (PRWEB) September 22, 2006
Research published in The Journal of Sexual Medicine and presented at the 12th World Congress of the International Society for Sexual Medicine in Cairo, Egypt is unique in that the data is from a head to head trial of PDE5 inhibitors used to treat patients with erectile dysfunction (ED), designed to minimize bias toward either study drug. The study was a randomized, double-blind, crossover, head-to-head clinical trial that compared vardenafil and sildenafil treatment in men with ED and diabetes, hypertension, and/or hyperlipidemia. The results demonstrated that vardenafil achieved nominal statistical superiority over sildenafil for several frequently used efficacy measures, and non-inferiority of vardenafil to sildenafil as measured by various assessments of patient satisfaction and patient preference.
A total of 1,057 men participated in the study, which involved treatment using each drug for four weeks, with a one-week washout period in between. Patients were asked: “Overall, which medication do you prefer?” along with 11 other preference questions relating to their ED treatment. Additional efficacy assessments using established scales were also used in analysis.
Data showed that 38.9% preferred vardenafil compared to 34.5% sildenafil (26.6% had no preference). Vardenafil was significantly superior to sildenafil in terms of erectile function, intercourse satisfaction and overall satisfaction. There were also a significant higher percentage of positive responses for vardenafil with regards to erection hardness for penetration, maintenance of erection, maintenance until completion, and erection confidence.
“This study represents an important step forward in our understanding of the clinical differences between PDE5 inhibitors, confirming the efficacy of vardenafil for men with erectile dysfunction,” explains Irwin Goldstein, study co-author and Editor-in-Chief of The Journal of Sexual Medicine.
There are currently three PDE5 inhibitors available to treat ED: sildenafil, tadalafil and vardenafil, all of which have previously demonstrated efficacy and tolerability in a range of patient populations, according to researchers.
Data from head-to-head clinical trials, like this one, are scarce. However, results from studies such as this should help clinicians to differentiate among sildenafil, vardenafil, and tadalafil and to select the most appropriate for individual patients.
This study is published in The Journal of Sexual Medicine. Media who would like to receive a PDF of the study should contact: medicalnews @ bos.blackwellpublishing.net.
The Journal of Sexual Medicine publishes multidisciplinary basic science and clinical research to define and understand the scientific basis of male and female sexual function and dysfunction. As the official journal of the International Society for Sexual Medicine, it provides healthcare professionals in sexual medicine with essential educational content and promotes the exchange of scientific information generated from experimental and clinical research. For more information visit: http://www.blackwellpublishing.com/jsm.
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‘Spicing’ up your love life, with spice
GUELPH, Ontario, March 28 (UPI) — For those looking to spice up their love life, Canadian researchers suggest adding the herb ginseng or the spice saffron to their diet. Read more on UPI
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An aphrodisiac is a substance that increases sexual desire. The name comes from Aphrodite, the Greek goddess of sexuality and love. Throughout history, many foods, drinks, and behaviors have had a reputation for making sex more attainable and/or pleasurable. However, from a historical and scientific standpoint, the alleged results may have been mainly due to mere belief by their users that they … Read more on Environmental News Network
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